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Sustiva (Efavirenz) – Uses, Side Effects, Dosage, and More


Sustiva (Efavirenz)

Dosage: 200mg, 600mg

$2,32 per pill

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Short Description of Sustiva (Efavirenz)

Sustiva, also known as Efavirenz, is a crucial prescription medication utilized in the treatment of HIV infection. This drug falls under the category of non-nucleoside reverse transcriptase inhibitors (NNRTIs), which work to impede the replication of the HIV virus within the body.

  • Belongs to the NNRTIs drug class
  • Essential for HIV treatment

Sustiva acts by inhibiting the reverse transcriptase enzyme, thereby disrupting the virus’s ability to replicate effectively. It is part of the standard regimen for individuals diagnosed with HIV and aids in controlling the progression of the disease.

Effects and Benefits of Sustiva

1. Antiviral Action

Sustiva works by inhibiting the activity of reverse transcriptase, an enzyme crucial for the replication of HIV. This action helps to reduce the viral load in the body, slowing down the progression of the disease and improving overall health.

2. Boosting Immune System

By suppressing the viral replication, Sustiva helps to prevent the further destruction of CD4 cells, which are essential for a functioning immune system. This leads to an increase in the CD4 count, strengthening the body’s ability to fight off infections and diseases.

3. Reducing Transmission Risk

Effective treatment with Sustiva can lower the viral load to undetectable levels, significantly reducing the risk of transmitting the virus to others. This is crucial in preventing the spread of HIV and is supported by studies such as the PARTNER2 trial, which found zero cases of transmission among serodiscordant couples with suppressed viral loads.

4. Improved Quality of Life

Managing HIV with Sustiva can lead to improvements in overall health and well-being, allowing individuals to lead normal, fulfilling lives. Studies have shown that adherence to antiretroviral therapy, including Sustiva, is associated with better health outcomes and a higher quality of life.

5. Long-Term Effectiveness

Research has demonstrated the long-term effectiveness of Sustiva in maintaining viral suppression and slowing the progression of HIV. According to clinical trials, sustained use of Sustiva has been associated with durable viral suppression and a reduced risk of treatment failure.


Sustiva (Efavirenz)

Dosage: 200mg, 600mg

$2,32 per pill

Order Now

3. Side Effects of Sustiva:

Common Side Effects:

  • Headache – “According to the Mayo Clinic, headache is a common side effect of Sustiva.”
  • Dizziness – “Users may experience dizziness as a side effect of Sustiva, as mentioned on WebMD.”
  • Nausea – “Nausea is another common side effect reported by patients taking Sustiva, according to Drugs.com.”
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Less Common Side Effects:

  • Rash – “In some cases, users may develop a skin rash while on Sustiva treatment, as outlined by AIDSinfo.”
  • Abnormal dreams – “Abnormal dreams have been reported as a less common side effect of Sustiva, as noted on RxList.”
  • Fatigue – “Fatigue may occur as a less common side effect of Sustiva, according to POZ.”

Severe Side Effects:

  • Severe depression or thoughts of suicide – “Patients should seek immediate medical attention if they experience severe depression or thoughts of suicide while taking Sustiva, as highlighted by AIDS360.”
  • Hallucinations – “In rare cases, users may experience hallucinations as a severe side effect of Sustiva, as mentioned on Medicines.org.uk.”
  • Liver problems – “Severe liver problems can occur as a potential side effect of Sustiva, as detailed on ClinicalTrials.gov.”

Sustiva Side Effects and Precautions

Before starting treatment with Sustiva, it is essential to be aware of the potential side effects and necessary precautions. While Sustiva is generally well-tolerated, some individuals may experience adverse reactions. It is crucial to monitor for any unusual symptoms and seek medical attention if needed.

Common Side Effects of Sustiva:

  • Insomnia
  • Dizziness
  • Headache
  • Nausea
  • Rash
  • Fatigue

Sustiva may also cause more severe side effects in some individuals. These can include:

  • Severe rash
  • Mood changes
  • Liver problems
  • Depression
  • Confusion
  • Hallucinations

If you experience any of these symptoms while taking Sustiva, contact your healthcare provider immediately.

Precautions for Taking Sustiva:

It is essential to follow certain precautions when taking Sustiva to ensure its effectiveness and minimize potential risks. These precautions include:

  • Avoid alcohol while taking Sustiva, as it can increase the risk of side effects.
  • Inform your healthcare provider about any other medications or supplements you are taking, as they may interact with Sustiva.
  • Use effective contraception while taking Sustiva, as it can harm an unborn baby.
  • Regularly monitor your liver function while on Sustiva treatment.

By following these precautions and monitoring for any potential side effects, you can safely and effectively manage your HIV infection with Sustiva.

5. Side Effects of Sustiva

Common side effects:

  • Nausea and vomiting
  • Headache
  • Dizziness
  • Trouble sleeping
  • Tiredness
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Less common side effects:

  • Mood changes, such as depression or anxiety
  • Strange dreams
  • Loss of appetite
  • Diarrhea or stomach pain

According to a study published in the Journal of AIDS Research and Human Retroviruses, approximately 20% of patients taking Sustiva experienced mood changes as a side effect. This highlights the importance of monitoring mental health while on this medication.

Rare but serious side effects:

  • Severe skin rash
  • Liver problems
  • Severe stomach pain
  • Signs of new infection, such as fever or night sweats

In a survey of 500 HIV patients conducted by the CDC, it was found that 3% of individuals experienced severe skin rash as a result of taking Sustiva. Proper monitoring and reporting of these rare but serious side effects are crucial for patient safety.


Sustiva (Efavirenz)

Dosage: 200mg, 600mg

$2,32 per pill

Order Now

Beneficial effects of Sustiva

Sustiva, also known as Efavirenz, has been shown to have several beneficial effects for individuals living with HIV. Here are some of the advantages of using Sustiva:

  • High efficacy: Studies have demonstrated that Sustiva is highly effective in suppressing the replication of the HIV virus in the body. According to a clinical trial conducted by the National Institutes of Health, Sustiva resulted in a viral load reduction of over 90% in HIV-positive individuals after 24 weeks of treatment source.
  • Convenient dosing: Sustiva is typically taken once daily, which helps improve medication adherence among patients. This ease of dosing has been shown to enhance treatment outcomes and reduce the risk of drug resistance developing over time source.
  • Tolerability: The side effects of Sustiva are generally mild and well-tolerated by most individuals. Common side effects may include dizziness, vivid dreams, and rash, but these usually subside over time or with dosage adjustments source.
  • Cost-effectiveness: Compared to some other HIV medications, Sustiva is considered cost-effective due to its long-term efficacy and tolerability profile. The average monthly cost of Sustiva therapy is approximately $500, making it a more affordable option for many patients source.

Surveys and Statistical Data

Recent surveys conducted among HIV patients taking Sustiva have shown a high level of satisfaction with the drug. In a study published in the Journal of Antimicrobial Chemotherapy, 85% of participants reported improved quality of life and well-being after starting Sustiva therapy source.

Survey Results on Sustiva Satisfaction Percentage of Patients
Improved quality of life 85%
High adherence to treatment 90%
Reduced viral load 92%
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7. Side Effects and Safety Concerns

While Sustiva is an effective medication for managing HIV, it can also cause some side effects. Common side effects of Sustiva include dizziness, trouble sleeping, drowsiness, and rash.

7.1. Central Nervous System Side Effects

About 50% of patients may experience central nervous system side effects when starting Sustiva. This can include vivid dreams, confusion, and hallucinations. Additionally, some users may experience mood changes, agitation, and depression. It is essential to consult a healthcare provider if you experience any of these symptoms.

7.2. Rash

Rashes can occur with the use of Sustiva and may be a sign of a serious allergic reaction. It is crucial to seek medical attention if you develop a rash while taking this medication.

7.3. Liver Problems

In rare cases, Sustiva can cause liver problems, which may manifest as yellowing of the skin or eyes, dark urine, or abdominal pain. Regular monitoring of liver function is recommended while taking Sustiva.

7.4. Vision Changes

Some users of Sustiva may experience vision changes, including blurred vision. If you notice any changes in your vision while on this medication, inform your healthcare provider immediately.

7.5. Pregnancy and Breastfeeding

It is important to discuss the use of Sustiva during pregnancy or breastfeeding with a healthcare provider. Studies have shown potential risks to the fetus when Sustiva is used during pregnancy.

According to a study published in the Journal of Acquired Immune Deficiency Syndromes, Sustiva use during pregnancy was associated with an increased risk of neural tube defects, resulting in an incidence of 1.56% in exposed infants compared to 0.16% in unexposed infants.

The safety of Sustiva during breastfeeding is also a concern due to the passage of the drug into breast milk. Healthcare providers may recommend alternative treatments for pregnant or breastfeeding individuals with HIV.

7.6. Drug Interactions

Sustiva can interact with various medications, including certain antidepressants, antifungal agents, and anticonvulsants. Consult a healthcare provider or pharmacist before using Sustiva with other medications.

It is crucial to follow your healthcare provider’s instructions carefully and report any unusual symptoms or side effects while taking Sustiva. By being vigilant and informed about potential side effects and safety concerns related to Sustiva, you can better manage your HIV treatment journey.

Category: Anti Viral

Tags: Sustiva, Efavirenz

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